CAS No: | 536-43-6 | EINECS: | 208-633-6 |
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Molecular Formula: | C18H28ClNO2 | Molecular Weight: | 325.87 |
Storage: | Cool And Dry Place | Transport Package: | Transport Package |
Shelf Life: | 1kg/Bag; 25kg/Drum | ||
Highlight: | C18H28ClNO2 Dyclonine Hydrochloride,536-43-6 Dyclonine Hcl,C18H28ClNO2 Dyclonine Hcl |
Dyclonine Hydrochloride For Raw Material For Medicine C18H28ClNO2
Properties & Specification
Dyclonine Hydrochloride is the hydrochloride salt of Dyclonine, an unclassified compound with local anesthetic effect. Dyclonine reversibly binds to activated sodium channels on the neuronal membrane, thereby decreasing the neuronal membrane's permeability to sodium ions, leading to an increased threshold for excitation. This reversibly stabilizes the membrane and inhibits depolarization, leading to the failure of a propagated action potential and subsequent conduction blockade. This results in a transient and reversible loss of sensation in a localized area of the body.
Item | Specifications | Results |
Appearance | A white crystalline powder | White crystalline powder |
Identification | IR; HPLC | Conforms |
Sulphates | NMT0.05% | Conforms |
Toluene | NMT890ppm | Not detected |
Methanol | NMT3000ppm | Not detected |
Related substances(TLC) | NMT1.0% | Conforms |
Loss on drying | NMT0.5% | 0.07% |
Sulphated ash | NMT0.1% | 0.09% |
Ammonium | NMT0.08% | Conforms |
Heavy metals | NMT0.001% | Conforms |
Assay(On dry basis) | 99.0%-101.0% | 99.58% |
Microbiology | Total bacterial count:<1000CFU/g | 30CFU/g |
Total Fungus count: <100CFU/g | <10 CFU/g | |
Escherichia coli:Not detected | Not detected |
Packing and Storage(warehouse, protected from light, and sealed; should be lightly loaded and unloaded during transportation to prevent internal packaging from rupturing.)