K Value: | 15.3-18.4 | Moisture: | 5.0% Max |
---|---|---|---|
NVP: | 0.1% Max | PH(5% Solution): | 3.0-7.0 |
Highlight: | Polyvinylpyrrolidone PVP K17,Water Soluble Polymer Povidone K17,Povidone K17 Powder |
Water-Soluble Polymer Polyvinylpyrrolidone PVP K17 White Powder Povidone K17
Chemical Description
Polyvinylpyrrolidone (abbr. PVP)
CAS No. 9003-39-8
INCI Name PVP
Molecular Formula (C6H9NO)n
Characteristics
A white to yellowish white , hygroscopic powder;
Freely soluble in water and a variety of organic solvents;
Specification Ph Eur ,USP/NF,BP,JP
No |
Tests | K15 | K17 | K25 | K30 | K90 |
1 | Identification, A B C D E | Complies | ||||
2 | Appearance of solution | Clear, ≤B6,BY6 or R6 | ||||
3 | PH(in 5% solution) | 3-5 | 3-5 | 3-5 | 3-5 | 4-7 |
4 | Viscosity, as K-value | 13-17 | 14.5-19.5 | 22.5-27 | 27-32.4 | 81-97 |
5 | Aldehyde, ppm | ≤500 | ≤500 | ≤500 | ≤500 | ≤500 |
6 | Peroxides (as H2O2), ppm | ≤400 | ≤400 | ≤400 | ≤400 | ≤400 |
7 | Formic acid,% | ≤0.5 | ≤0.5 | ≤0.5 | ≤0.5 | ≤0.5 |
8 | Hydrazine, ppm | ≤1 | ≤1 | ≤1 | ≤1 | ≤1 |
9 | Impurity A (VP),ppm | ≤10 | ≤10 | ≤10 | ≤10 | ≤10 |
10 | Impurity B (2-pyrrolidone ),% | ≤3.0 | ≤3.0 | ≤3.0 | ≤3.0 | ≤3.0 |
11 | Heavy metals, ppm | ≤10 | ≤10 | ≤10 | ≤10 | ≤10 |
12 | Water, % | ≤5.0 | ≤5.0 | ≤5.0 | ≤5.0 | ≤5.0 |
13 | Sulphated ash,% | ≤0.1 | ≤0.1 | ≤0.1 | ≤0.1 | ≤0.1 |
14 | Assay, as Nitrogen content,% | 11.5-12.8 | 11.5-12.8 | 11.5-12.8 | 11.5-12.8 | 11.5-12.8 |
Application(USP/EP)
Binder for tablets, granules and hard gelatin capsules;
Bioavailability enhencement, Film formation, Solubilization;
Injection preparations, Stabilization of suspensions, Drug stabilization;
Dietetic tablets in neutritional products;
Packaging and Storage
Packed in 25, 50 kg fiber or plastic drum, inner lined with PE bags;
Stored in dry place at room temperature;